chronic renal failure
Noun: A long-term, progressive condition characterized by the gradual and permanent loss of kidney function over a period of months or years. It results from a variety of systemic disorders and leads to the accumulation of waste products and fluid in the body.
"Chronic renal failure" is a medical term used to describe the irreversible deterioration of kidney function. It is a clinical diagnosis. - It is often abbreviated as CRF. - It is a stage of chronic kidney disease (CKD), typically referring to advanced loss of function. - The term describes the condition itself, not a single event.
- The patient was diagnosed with chronic renal failure due to long-standing hypertension.
- Management of chronic renal failure often involves dietary restrictions and medication.
- Chronic renal failure can eventually progress to end-stage renal disease, requiring dialysis.
- Staging: In modern clinical practice, "chronic renal failure" is often described within the framework of the five stages of chronic kidney disease (CKD), with failure typically corresponding to stages 3-5.
- Synonymous Context: The term is sometimes used interchangeably with "chronic kidney failure" or "advanced chronic kidney disease."
- Chronic Kidney Disease (CKD): A broader term encompassing all stages of kidney damage and function loss, from mild (stage 1) to failure (stage 5).
- End-Stage Renal Disease (ESRD): The final, most severe stage of chronic renal failure where kidney function is minimal or absent, requiring renal replacement therapy (dialysis or transplant).
- Uremia: The clinical syndrome associated with the toxic buildup of waste products in the blood due to advanced renal failure.
- Chronic kidney failure
- Advanced chronic kidney disease
The definition specifies that chronic renal failure "can result from a variety of systemic disorders." This distinguishes it from acute kidney injury, which is often caused by a specific, sudden event. Common underlying causes include diabetes mellitus, hypertension, glomerulonephritis, and polycystic kidney disease.
- renal failure that can result from a variety of systemic disorders